High Blood Sugar Levels May Impact Male Sexual Health, Study Finds

Recent findings presented at the Endocrine Society's annual meeting, ENDO 2025, indicate that elevated blood sugar levels can negatively affect men's sexual health. While the study has yet to undergo peer review, it suggests that even modest increases in blood sugar, remaining below diabetic thresholds, can reduce sperm motility and impair erectile function.

The research involved an analysis of health records belonging to 110 adult males, all of whom were living with obesity or type 2 diabetes. These individuals were undergoing treatment with weight-loss medications and were not receiving any testosterone or hormonal therapy. Following a 10% reduction in body weight, researchers observed an increase in the proportion of men with normal total and free testosterone levels, which rose from 53% to 77%.

As per this preliminary research, which took place in San Francisco, elevated blood sugar can lead to a decline in testosterone levels. Although testosterone does not directly determine erectile function, it is closely related to libido, which is an essential factor in sexual performance.

Notably, high glucose levels can inflict damage on both nerves and blood vessels, critical components for successfully achieving and maintaining an erection. This damage can consequently result in erectile dysfunction.

Experts recommend a balanced diet rich in whole foods and fibre to help regulate blood sugar levels and mitigate inflammation. Regular physical exercise is also encouraged as it enhances insulin sensitivity and supports weight loss efforts. Techniques such as meditation and yoga may further improve mental and emotional well-being, which also play a vital role in sexual health.

Certain medications like semaglutide, liraglutide, and tirzepatide are effective in managing blood sugar levels. Dr Shellsea Portillo Canales, an endocrinology fellow at SSM Health St. Louis University Hospital, remarked, "While it is well known that weight loss from lifestyle changes or bariatric surgery increases testosterone levels, the impact that anti-obesity medications may also have on these levels has not been widely studied."

Dr Canales further stated, "Our study is among the first to provide compelling evidence that low testosterone can be reversed with the use of commonly prescribed anti-obesity medications."

This research underscores the importance of maintaining healthy blood sugar levels for not just physical well-being but also sexual health. Continued exploration in this field may lead to more informed approaches for managing men's health issues associated with elevated blood sugar.